Forty-seven nursery school children are dead in Egypt after a train crashed into their bus at a train crossing.
The governor of the central province of Assiut told state television that 13 children were also injured in the crash.
The bus, which was taking 60 children on a trip organized by their nursery, was struck on a railway crossing in Manfalut, 356 kilometers south of Cairo.
The children were aged between 4 and 6.
Transport Minister Rashad al-Metini has resigned in the wake of the tragedy, saying he "accepts responsibility" for the accident.
Egyptian President Muhammad Morsi has also accepted the resignation of the Egyptian Railway Authority head.
Egypt's railway system has a poor safety record, mostly blamed on badly maintained equipment and poor management.
The railway's worst disaster took place in February 2002 when a train heading to southern Egypt caught fire, killing 363 people.
Based on reporting by dpa, AP, and AFP