U.S. Vice President Joe Biden says his son Beau has died after battling brain cancer.
A White House statement said, "The entire Biden family is saddened beyond words. We know that Beau's spirit will live on in all of us, especially through his brave wife, Hallie, and two remarkable children, Natalie and Hunter."
Beau Biden, 46, a former Delaware attorney general, was reported earlier this month to be undergoing treatment at Walter Reed Army Medical Center outside Washington.
After eight years as attorney general, Beau Biden joined the investor law firm Grant & Eisenhofer in 2015.
He served a yearlong tour in Iraq as a captain in the Delaware Army National Guard and underwent surgery at a cancer center in Texas last year.
He suffered a mild stroke in 2010.
President Barack Obama, in a separate statement, expressed his condolences late May 31.
"Michelle and I are grieving tonight," Obama said.
The vice president has faced family tragedy before. Shortly after winning election to the U.S. Senate in 1972, his wife Neilia and three children were in a car crash.
Neilia and their daughter were killed, while their two sons, Beau and Hunter, were injured.
Based on reporting by Reuters and AP