Syrian opposition groups say a government missile attack near the capital, Damascus, has killed more than 40 people and wounded dozens of others.
The Local Coordination Committees group and the London-based Syrian Observatory for Human Rights (SOHR) say at least 10 surface-fired missiles landed in the rebel-held town of Douma early on October 30, with some of them hitting a market area.
Those reports were also confirmed by a Douma-based activist network.
SOHR head Rami Abdel Rahman told AFP that at least 100 people had been wounded in the attack and that people were still being pulled from destroyed buildings.
A suburb east of Damascus, Douma has often been the target of government air strikes and barrel-bomb attacks.
Douma is part of Eastern Ghouta, the opposition's largest stronghold in Damascus Province.
The attack comes one day after air strikes by Syrian planes also damaged another market and hospital in Douma, killing nine people, SOHR reported.
The missile barrage came as diplomats from 17 countries met in Vienna in an effort to end the fighting in Syria.