Final Summary

-- Iran and major global powers sealed a landmark deal to curb Tehran's nuclear program in exchange for sanctions relief, taking a giant step to end a confrontation that has poisoned ties, isolated the Islamic nation, and raised the specter of a new war in the Middle East.

-- U.S. President Barack Obama has called Benjamin Netanyahu to assuage Israeli concerns over the landmark deal.

-- Obama's administration still faces potential hurdles in the U.S. Congress, where lawmakers offered reactions to the deal ranging from wariness to outrage.

-- Russian President Vladimir Putin, whose country has been Tehran's strongest supporter in the UN Security Council and vocally opposes U.S. and EU sanctions against Iran, said the deal would contribute to combatting terrorism in the Middle East.

-- From potentially stoking a Middle East arms race, to enabling political reforms in Iran, to undercutting Russia’s energy might by freeing up massive oil and gas supplies, here are some possible implications of the agreement.

-- Find a comprehensive timeline of the Iran nuclear talks here.

-- More about the origins of Iran's nuclear program here.

-- For reaction on the streets of Tehran, click here

-- For Israeli reactions to the deal, click here and here

NOTE: Times are stated according to local time in Tehran