A U.S. drone strike in Pakistan's tribal region has reportedly killed at least 10 militants.
Four missiles hit a compound in Baland Khel area near the border between the Orakzai and North Waziristan districts.
Orakzai political administrator Khushal Khan said the compound was owned by a commander of the militant Hafiz Gul Bahadur group that operates in North Waziristan.
Most of the those killed were said to be Afghans.
Pakistan's Foreign Ministry later said in a statement it had informed the U.S. Embassy that "drone strikes on Pakistani territory were a clear violation of international law and Pakistan's sovereignty."
Also in Orakzai, a roadside bomb ripped through a commuter van, killing four people and wounding nine.
Officials said the blast occurred in the Sunzu Darra area, where the military is involved in operations against Taliban and Al-Qaeda militants.
Reports say the explosives were rigged to a donkey cart.
No group claimed responsibility for the bombing, but the Taliban and other Islamist militants routinely target security forces with improvised explosive devices (IED) across the tribal region on Afghanistan's border.
Two other bomb blasts in Pakistan's restive southwestern Balochistan Province killed at least 13 people.
Senior police officer Ghulam Ali Lashari said the first bomb went off outside a market in the town of Sibi, killing 10 and wounding 24 people.
The blast also destroyed several shops in the town, which lies about 150 kilometers east of Quetta, the provincial capital.
Some 200 kilometers away in the town of Dera Bugti, a roadside bomb struck a vehicle carrying security personnel, killing three officers and wounding two.
No one immediately claimed responsibility for the bombings, but ethnic Baloch separatists have long waged a low-level insurgency in the resource-rich region. Islamist militants, including the Taliban, also operate in Balochistan.