The mostly young protesters chanted slogans against the World Bank and the International Monetary Fund, which sponsor the Heavily Indebted Poor Countries (HIPC) program.
They chanted slogans such as "World Bank, Get Out! HIPC, No Way!"
This was the fourth such protest rally held in Bishkek since talks on joining the program started in the Kyrgyz capital on November 29.
The government says joining HIPC will help write off a substantial part of the country's $2 billion external debt. But critics fear the program will give the World Bank and the IMF too much control over the Kyrgyz economy.
(RFE/RL's Kyrgyz Service, president.kg, 24.kg)